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Dogs, cats and horses
May Be Prescribed by Vets for:
Dogs and cats: Congestive heart failure (CHF), pulmonary edema, uremia, hyperkalemia, hypertension.
Horses: Exercise induced pulmonary hemorrhage, acute renal failure, edema due to a variety of causes.
Furosemide is commercially available as tablets 12.5mg,
20mg, 40mg, 50mg, 80mg, oral solution 8mg/ml, 10mg/ml,
and injection 10mg/ml, 50mg/ml.
Search for Available Dosage Forms
Furosemide may be administered orally, intramuscularly, subcutaneously, or intravenously. Onset of action after oral administration is approximately one hour. Onset of action after intravenous administration is five minutes with peak effect at approximately 30 minutes. Constant rate infusion may be helpful in the initial phase of treatment of animals with life-threatening CHF.
Furosemide is used in dogs and cats to promote diuresis and manage fluid retention. It is commonly used to treat pulmonary edema due to CHF. Other uses include diuresis in acute renal failure, management of ascites, hypercalcemia, or hyperkalemia. Although furosemide also lowers blood pressure through vasodilation, it is not considered a primary treatment for hypertension.
Cats are more sensitive to furosemide than dogs or other species and may need lower doses. Cats are also more likely to develop hypokalemia, azotemia and ototoxicity.
Furosemide is used in general equine practice to manage fluid retention and edema. It is commonly used in racehorses to reduce the incidence of exercise-induced pulmonary hemorrhage (EIPH) and epistaxis. The mechanism of action is through the dose-dependent reduction in right atrial, pulmonary arterial, and pulmonary capillary pressures. Furosemide has been shown to cause bronchodilation, which may also play a role in the prevention of epistaxis.
There are a number of possible drug interactions with furosemide:
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
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