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Centrally acting emetic
May Be Prescribed by Vets for:
No veterinary approved products in the United States.
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Emetics are an important early treatment for some orally ingested toxins. Emetics generally remove only 40-60% of the stomach contents and are useful in the first four hours after ingestion. Apomorphine is metabolized in the liver and excreted in urine.
Apomorphine is the emetic of choice in dogs. It commonly is given parenterally (IM or IV) or topically in the conjunctival sac. When given intravenously, vomiting occurs rapidly. After intramuscular injection, vomiting should occur within five minutes. Conjunctival administration usually is effective although not as quickly or reliably as parenteral administration. If vomiting does not occur after one dose, repeated doses are unlikely to be effective and increase the likelihood of undesirable side-effects or toxicity. Apomorphine is poorly absorbed orally.
Overdose with apomorphine can cause respiratory and cardiac depression, CNS stimulation or depression and protracted vomiting. Naloxone may be used to reverse CNS and respiratory signs, but will not diminish the vomiting.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
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This content is intended for counseling purposes only. This content is informational/educational and is not intended to treat or diagnose any disease or patient. No claims are made as to the safety or efficacy of mentioned preparations. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. All product and company names are trademarks™ or registered® trademarks of their respective holders. Use of them does not imply any affiliation with or endorsement by them.