Enalapril Maleate for Dogs and Cats
General Drug Information and Indications
How to Give this Medication
Search for Available Dosage Forms
Enalapril is a drug that is used in dogs and cats with heart and or kidney problems. Enalapril causes small blood vessels to relax (vasodilation). This makes it easier for blood to circulate, which then decreases blood pressure and decreases the work load on the heart. Enalapril is frequently used with other heart medications, such as diuretics or beta blockers. Enalapril is also used for the treatment of high blood pressure (hypertension) in dogs.
Enalapril is FDA approved for use in dogs, but not in cats or other companion animals. When the appropriate form or dose of this drug is not available through a veterinary pharmaceutical manufacturer, it may be compounded by a specialty pharmacy.
Give this medication to your pet exactly as your veterinarian prescribes. If you miss giving your pet a dose of enalapril, give the next dose as soon as you remember or, if it is close to the next scheduled dose, return to the regular schedule. Do not double dose to catch up.
Wash your hands after giving your pet this medication.
Be sure to discuss any side effects with your veterinarian immediately.
The most common side effects are low blood pressure, dizziness, weakness and stomach upset.
Less common side effects include kidney damage and changes in blood potassium levels.
Keep this and all drugs out of reach of children. Enalapril is a prescription drug and should be used according to your veterinarian’s directions. It should only be given to the animal for which it was prescribed. Do not give this medication to a person.
Pets receiving enalapril will need regular monitoring, including blood chemistry, kidney function and blood pressure.
Although enalapril is used to treat some forms of chronic kidney failure, there are instances in both dogs and cats where enalapril therapy has worsened the underlying kidney problems.
Enalapril is eliminated from the body by the kidneys. Animals with decreased kidney function will need additional monitoring.
Enalapril may change the insulin requirements in diabetic animals. It is likely that a diabetic pet will need additional monitoring.
Enalapril is metabolized to the active form in the liver. Pets with decreased liver function may not be able to adequately utilize this drug.
Enalapril should be avoided in pregnant or lactating animals.
Be sure to review with your veterinarian any medications or supplements your pet may be receiving. Pets receiving enalapril may be on multiple medications because of the severity of their health problems. Careful monitoring and adjustment of drug doses and therapies may be necessary to achieve the right balance.
Diuretics, such as furosemide or spironolactone, and other vasodilators drugs may increase the incidence of low blood pressure or change blood potassium levels.
Nonsteroidal anti-inflammatory drugs, including aspirin, should be avoided in animals on enalapril because of increased risk of kidney damage.
If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A.’s Animal Poison Control Center at 888.426.4435. Always bring the prescription container with you when you take your pet for treatment.
If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222.
Different strengths or dosage forms of enalapril maleate may have different storage requirements. Read the labeling or ask your pharmacist for the storage requirements of the prescription you receive.
About the Author
Dr. Barbara Forney is a veterinary practitioner in Chester County, Pennsylvania. She has a master's degree in animal science from the University of Delaware and graduated from the University of Pennsylvania School of Veterinary Medicine in 1982.
She began to develop her interest in client education and medical writing in 1997. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.
Dr. Forney is an FEI veterinarian and an active member of the AAEP, AVMA, and AMWA.
You can purchase books by Dr. Forney at www.exclusivelyequine.comThe information contained on this site is general in nature and is intended for use as an informational aid. It does not cover all possible uses, actions, precautions, side effects, or interactions of the products shown, nor is the information intended as medical advice or diagnosis for individual health problems or for making an evaluation as to the risks and benefits of using a particular product. You should consult your doctor about diagnosis and treatment of any health problems. Information and statements have not been evaluated by the Food and Drug Administration ("FDA"), nor has the FDA approved the products to diagnose, cure or prevent disease.
Wedgewood Pharmacy compounded veterinary preparations are not intended for use in food and food-producing animals.